Welcome to join!
Professor Alastair Murchie, Professor and PhD Supervisor of the Institute of Biomedical Sciences, Fudan University, graduated from the Department of Biochemistry and Molecular Biology, University of Dundee, UK, in 1994, and worked as a postdoctoral fellow and senior researcher at the Department of Biochemistry, University of Dundee, UK, in 1994-1998, and as Chief R&D Officer of Ribotargets, a new drug development company in Cambridge, UK, in 1998-2003. Professor Murchie's main research interests are (1) Advanced structure and biological function of nucleic acids, including the discovery of novel riboswitches […]
Dr. Dali Han applies epigenetic techniques, chemical biology tools, and bioinformatics methods to study the regulatory mechanisms of RNA modification. He has gradually formed a characteristic research system that combines RNA epigenomics, single-cell transcriptomics, and spatial transcriptomics, achieving a series of cutting-edge progresses: In terms of regulatory theory, he has revealed new transcriptional regulatory mechanisms of chromatin structure and histone modifications directly affected by caRNA m6A modification; In terms of pathogenic mechanisms, he has systematically analyzed the functional dysregulation and RNA modification abnormalities in the tumor microenvironment, including tumor cells, dendritic cells, macrophages, and T cells, identified multiple new targets for immunotherapy and developed small molecule inhibitors […]
Jewel-like memories
Structure and mechanism of a methyl transferase ribozyme
Computational modeling of RNA 3D structures and interactions with the use of experimental data
More details！
Dr. Alastair Murchie, Fudan University, China, will give a talk on Cofactor Binding Triggers Rapid Conformational Remodelling of the Active Site of a Methyltransferase Ribozyme.
Professor Alastair Murchie, Professor and PhD Supervisor of the Institute of Biomedical Sciences, Fudan University, graduated from the Department of Biochemistry and Molecular Biology, University of Dundee, UK, in 1994, and worked as a postdoctoral fellow and senior researcher at the Department of Biochemistry, University of Dundee, UK, in 1994-1998, and as Chief R&D Officer of Ribotargets, a new drug development company in Cambridge, UK, in 1998-2003. Professor Murchie's main research interests are (1) Advanced structure and biological function of nucleic acids, including the discovery of novel riboswitches and ribozymes, their structure and function, and their impact on gene expression and regulation, effects on gene expression and regulation, RNA modification and its biological functions, RNA epigenetics in disease and stem cells. (2) Interaction between non-coding RNAs and small molecules regulates the expression of antibiotic resistance genes. He was awarded the 2015 Shanghai Magnolia Memorial Prize.
For more information about her outstanding work, please visit her profile at
https://ibs.fudan.edu.cn/ibsen/05/99/c39095a460185/page.htm
Time(China): 2024-6-27 19:00
Time(UK): 2024-6-27 12:00
Tencent Meeting：284-568-908
bilibili live link:
https://live.bilibili.com/26427894
,
Welcome to follow the Guangzhou RNA club official account GzRNA, we will see you on May 23rd 2024!
Thanks to the International RNA Society, 博奥龙, 表观生物, 擎科生物, and 厚泽生物 for their sponsorship support!
More people are welcome!
Based on the applications of the pre-conference participants, 13 students have been awarded 2023 RNA Society trainee memberships for free. It is great to see the participation of students from different institutions, such as Lanzhou University, Nankai University, SIBS, Shanghai Jiaotong University, Melbourne University, Guangzhou Medical University, ShenZhen Bay Laboratory, Sun Yat-sen University and so on.
根据前期会议参与同学申请情况，13位同学已免费获得 2023 RNA Society trainee memberships。很高兴看到不同单位的同学申请，兰大，南开，SIBS，上交，墨尔本，广医，深圳湾，双鸭山等等。
We are organising RNA-Puzzles, which is a community-wide blind assessment of RNA 3D structure prediction. We also work on AI-based RNA design and RNA virus related research.
My lab is interested in the structure and function of nucleic acid aptamers, riboswitches, protein-nucleic acid interactions and catalytic activity in nucleic acids.
My research interests focus on the development and application of experimental and computational methods to discover novel classes of ncRNAs and their functions and mechanisms.
We are interested in eluciding the mechanisms and regulatory roles of RNA modifications on different classes of RNAs through close integration of bioinformatic method development with biochemical experiments.
More way to join
© 2022 Guangzhou RNA club.
We are part of the Guangzhou International Bioland.
Contact:
Building B2, Guangzhou Laboratory
96 Xingdao South Road, Guangzhou International Bio Island,
Haizhu District, Guangzhou, Guangdong, China. (Maps)
Guangzhou RNA club